The below 2019 review looks at the use of platelet rich plasma (PRP) injection treatment for knee osteoarthritis.
Platelets contain a high number of cytokines and bioactive protein growth factors which are believed to be able to effectively slow down the degeneration process or joints and may even initiate chondrogenesis (the new formation of cartilage cells). The recent review concluded that the scientific literature to date shows promising effects of PRP treatment in tissue healing based on clinically and scientifically described studies, and its effectiveness as a therapeutic agent is very valued. Studies have shown that PRP therapy increases the anabolic capacity of injured cartilage hence repairing the damage. PRP treatment can also be considered as an effective therapeutic agent to slow the progression of degenerative changes and delay the onset of irreversible damage, along with aiming to prevent or delay surgical intervention. Recent literature supports the use of PRP with results substantiating as the most effective conservative treatment measure for Osteoarthritis.
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