Updates in Regenerative Medicine in Osteoarthritis
Comparing Intra-articular Injections of Leukocyte-Poor Platelet-Rich Plasma Versus Low-Molecular Weight Hyaluronic Acid for the Treatment of Symptomatic Osteoarthritis of the Hip: A Double-Blind, Randomised Pilot Study
Hyaluronic acid (HA) and leukocyte-poor platelet-rich plasma (LP-PRP) are 2 popular successful nonoperative treatment options that have been studied in patients with hip osteoarthritis (OA).
Methods: A total of 34 patients (36 hips) presenting with signs of hip OA were randomised to receive 3 blinded, weekly intra-articular injections of either LP-PRP or LMW-HA. Patients were prospectively evaluated before injections and at 6 weeks and then at 3, 6, 12, and 24 months. The primary outcome, conversion to total hip surgery or a hip resurfacing procedure, was analysed along with secondary outcomes including pain score and hip range of motion.
Results: The final analysis included 33 hips in 31 patients. Significantly more patients converted to THA or a hip resurfacing procedure in the LMW-HA group than the LP-PRP group.There was no significant improvement or decline in any outcome scores within the LMW-HA group from before injections to 6 weeks or 3, 6, and 12 months. For the LP-PRP group, pain and function scores significantly improved from before injections to 6 weeks, andjoint scores significantly improved from before injections to 6 months. When comparing the difference between groups in internal rotation at 90° of hip flexion from before injections to 6 months, the LP-PRP group demonstrated a mean 5.0° improvement, while the LMW-HA group showed a mean 1.5° decrease.
Conclusion: Intra-articular hip injections of LP-PRP in patients with hip OA resulted in an improvement in pain and function scores and hip internal rotation at 6 months and delayed the need for total hip surgery or a hip resurfacing procedure compared with treatment with LMW-HA. A longer follow-up is necessary to further compare the effects of LP-PRP and LMW-HA injections in patients with hip OA.
GET IN TOUCH TO FIND OUT MORE OR SCHEDULE A FREE CONSULTATION
Don’t let pain, back pain,
joint damage, sports injuries or arthritis get in the way of allowing you to do what you want. Schedule a consultation at Dynamic Regenerative Medicine today, and let us treat your injury, provide pain relief and get you back to your full and active lifestyle. We have clinics operating out of Solihull (Henley-In-Arden) and Birmingham (Edgbaston).
Call us today 01564 330773
#HipPainTreatment #TreatmentForHipPain #HipOsteoarthritis #Injection #PRPTreatment #PlateletRichPlasma #Osteopath #PainRelief #SteroidInjection #CortisoneInjection #DynamicClinic #MedicalClinic #BackpainTreatment #SportsInjuryTreatment #Clinic