Joint Injection of Sodium Hyaluronate (Hyaluronic Acid) Combined with Corticosteroid (Cingal) for the Symptomatic Relief of Osteoarthritis of the Knee: A Randomised, Double-Blind, Placebo-Controlled Multicenter Clinical Trial Osteoarthritis (OA) is the most common joint disorder in the world, affecting around 40 million people in Europe. It is characterised by a reduced concentration of hyaluronic acid (HA) in the joint synovial fluid and a slow progressive degradation of j

Multiple platelet-rich plasma (PRP) injections are superior to single PRP injections or saline in osteoarthritis of the knee: the 2-year results of a randomised, double-blind, placebo-controlled clinical trial 2021. Journal of Orthoscopy and Sports Medicine What is osteoarthritis? Osteoarthritis of most joints, particularly of the knee is a major cause of chronic pain and musculoskeletal disability worldwide, alongside having huge impacts on society. Although there are many t

Estimated Time to Maximum Medical Improvement of Joint Injections in the Treatment of Knee Osteoarthritis - A Systematic Review. The purpose of this review of current literature is to evaluate maximum medical improvement and minimal clinically important difference of different injection therapies in the treatment of symptomatic knee osteoarthritis. Overall, 79 studies were evaluated, with a total of 8,761 patients. Injection therapy treatment consisted of - Corticosteroid inj

WHAT CAUSES KNEE SWELLING? A swollen knee is a common problem which can affect people of all ages. There are many reasons why the knees can become swollen which can cause huge pain and disability. It is very important to determine what is causing the knee to swell. It may an acute condition caused by a traumatic injury like in sports or activities, or a chronic condition which has progressively developed over time. It is also important to determine the location of the swellin

What is osteoarthritis? Osteoarthritis is a progressive, chronic degenerative disease that presents with varying degrees of joint cartilage damage, local inflammation and bone spurring. The progression of cartilage damage can often give pain, stiffness, swelling, poor mobility and can significantly affecting the quality of life. What is the treatment for osteoarthritis? Treatment is focused on reducing pain, improving mobility and preserving joint health by slowing the progre

Knee osteoarthritis is the most common progressive degenerative disease of joints caused by cartilage injury, degradation of the joint cartilage and bone spurribg. Various treatments are used in the treatment of arthritis symptoms of patients with knee osteoarthritis, including analgesics (pain killers), physical rehabilitation therapy and joint injections. Platelet‑rich plasma (PRP) is an autologous and multifunctional high concention of platelets of the blood, which is use