PRP is a natural substance that is injected into the affected tissue (joints, ligaments or tendons, for example), which is aimed to invoke a local inflammation and a “wound healing cascade”. This then to stimulate new collagen and initiate healing controlled by bioactive proteins found in platelets, plasma and white blood cells.
Platelet-rich plasma treatments stimulate high concentrations of stem cells into the affected area. Furthermore, collagen shrinks as it matures, and this tightens the damaged ligament or tendon, making it stronger (similarly to how collagen helps tighten aging, sagging skin).
PRP substance is very different than an ordinary blood sample because it contains much higher concentrations of platelets for example normal blood has about 6 percent platelets while PRP has about 94 percent. Platelets contain a number of proteins, inflammatory cells and other bioactive factors that initiate and regulate basic aspects of natural tissue healing, including those of the skin, connective tissue, etc.
Research shows that growth factors in platelet-rich plasma treatment helps stimulate cell replication, proliferation of Muscle cells, vascular growth, and insulin-like growth factor-1 that carry out repair of skeletal and muscular structures.
The main growth factors found in PRP include: platelet-derived, angiongensis, fibroblast, hepatocyte, insulin-like, epidermal and transforming factors. Three plasma proteins (fibrin, fibronectin and vitronectin) also contribute to the body’s repair matrix.
Sounds little too good to be true that something can be taken out of the blood concentrated and injected into a specific area to initiate improved recovery and healing. However, results speak for themselves…
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